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PR15054-2525 ug$315.00Buy Now | Add to Cart
 
Type: Protein
 
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Description/Data:

Oligodendrocyte myelin glycoprotein (OMgp) is a GPI-linked glycoprotein that exhibits multiple leucine-rich repeats and putative N- and O-linked glycosylation sites. It is primarily expressed on the surfaces of oligodendrocytes and large projection neurons, including Purkinje and pyramidal cells. OMgp binds a heterodimeric receptor complex consisting of Nogo R and NGF R/TNFRSF16 to collapse axonal growth cones and inhibit axonal and neurite outgrowth.