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MU AND KAPPA OPIOIDS INDUCE THE DIFFERENTIATION OF EMBRYONIC STEM CELLS TO NEURAL PROGENITORS. Eunhae Kim, Amy L. Clark, Alexi Kiss, Jason W. Hahn, Robin Wesselschmidt, Carmine J. Coscia and Mariana M. Belcheva.

JBC Papers in Press. Published on September 1, 2006 as Manuscript M603862200.

Image: A-D-Staining of Differentiated Stem Cells. D3 ES cells were maintained in serum/LIF/ME induced self-renewal conditions (undifferentiated cells, D3). Upon treatment with 1 µM RA they undergo differentiation (dD3). Cells were fixed and permeabilized. Treatments were followed by overnight incubation with polyclonal MOR-1 (C-terminus, 1:2500)