Olig 1,2,3

Olig1 and Olig2, which have been implicated in oligodendrogenesis, are expressed in the region of the ventral ventricular zone of late embryonic spinal cord where oligodendrocyte progenitors appear. Olig3 is transiently expressed in different types of progenitors of embryonic central nervous system and then disappears in the course of development. In adult, expression of Olig3 is primarily detected in neural tissues.

Image: Olig1,2,3 staining of rat corpus callosum after a demyelinating treatment. Image Courtesy of Dr. Juana Maria Pasquini, University of Buenos Aires.