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Human GFAP is a 49,749 dalton protein (432 amino acids) expressed in astrocytes. GFAP is an intermediate filament protein and acts as an intracellular structural component of the cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Various mutations of the GFAP gene in humans produce Alexander's disease, one of the leukodystrophies.
Image: A tissue section through an e18 mouse brain showing GFAP (brown) staining of radial glial cells (a.k.a. Bergman fiber of the cerebellum).
Neuronal-Glial Markers-Astrocytes, Glia, Microglia, Olidogodendrocytes, Progenitors and Schwann Cell Markers
Stem Cell Research Reagents -Stem cell research reagents Categories
Primary Neurons and Astrocytes-Primary human, rat and mouse neurons and astrocytes by Category