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Type: Mouse IgG
Applications: ICC; IHC
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Protein G Purified - liquid
Immunogen: CHO-derived recombinant human Matrilin-1. Ser23-Val496 Accession Number P21941.

Martilin-1, also named MATN1, Cartilage Matris Protein or CMP, is mainly expressed in cartilage.

Defects in Matrilin-1 lead to cartilage related diseases such as Adolescent idiopathic scoliosis (IS),  early onset osteoarthritis.and Relapsing Polychondritis which is an autoimmune disease that affects cartilage in the ear, nose, and respiratory tract.

Image: Matrilin-1 was detected in immersion fixed human mesenchymal stem cells differentiated into chondrocytes using Mouse Human Matrilin-1 Monoclonal Antibody  at 10µg/mL for 3 hours at room temperature. Cells were stained using the 577-conjugated Anti-Mouse IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cartilage matrix.