MHC I Streptamers are designed for fluorescent staining and/or magnetic isolation of antigen-specific cytotoxic CD8+ T cells. TheStreptamer® reagents are fully reversible, i.e. they can be completely removed from the labeled target cells so that the cells preserve their full biological function after staining or isolation. 

Modular Streptamer® technology : the MHC I-Streps can be associated either with a Strep-Tactin® fluorochrome for cell staining or with a Strep-Tactin® Magnetic Bead for cell isolation

Fluorescent Cell Staining

What you need:

Fluorescent Streptamers:

  • Antigen-specific MHC I-Strep®
  • Fluorochrome:Strep-Tactin®, PE or APC labeled

For removal of Streptamers:

  • Streptamer® Solution Set

Magnetic Cell Isolation

What you need:

Magnetic Streptamers:

  • Antigen-specific MHC I-Strep®
  • Strep-Tactin® magnetic nanobeads for cell isolation on magnetic columns

For removal of Streptamers:

  • Streptamer® Solution Set

MCH I Stemptamers -Fluorescent & Magnetic
Magnetic Cell Isolation
Isolation of antigen-specific cytotoxic CD8 T cells with reversible MHC I Streptamers

Staining and isolation of antigen-specific CD8+ T cells with reversible reagents

  
Magnetic Cell Isolation
Isolation of antigen-specific cytotoxic CD8 T cells with reversible MHC I Streptamers