Product Details
Catalog Number: 1224-10
Applications: BSM
Type: Modulator
Storage: Store at room temperature.
Shipping: Ambient
Format B: Powdered
Species Reactivity: All
Product Sizes
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10 mg$99.00Add to Cart

Biological Activity

A functional and membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP3) receptor antagonist (IC50 = 42 μM). Stimulates store-operated calcium (SOC) release at low concentrations (< 10 μM) and inhibits it at higher concentrations (up to 50 μM). Increases STIM-Orai channel conductance and limits ion selectivity. Modulator of TRP channels; blocks TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8 and TRPP2 and at higher concentrations stimulates TRPV1, TRPV2 and TRPV3. Also blocks specific gap channel subtypes.

Certificate of Analysis and Safety Data Sheet

Images

2-Aminoethoxydiphenylborane

2-Aminoethoxydiphenylborane