Product Details
Catalog Number: 699-10
Applications: BSM
Type: Ligand
Format B: Powdered
Species Reactivity: All
Product Sizes
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10 mg$159.00Add to Cart

Biological Activity

The most κ/μ-selective and among the most potent κ ligands known (25 times more potent than morphine in vivo).

Images
(±)-1-(3,4-Dichlorophenyl)acetyl-2-(­1-pyrrolidinyl)methylpiperidine hydrochloride

(±)-1-(3,4-Dichlorophenyl)acetyl-2-(­1-pyrrolidinyl)methylpiperidine hydrochloride

(±)-1-(3,4-Dichlorophenyl)acetyl-2-(­1-pyrrolidinyl)methylpiperidine hydrochloride

(±)-1-(3,4-Dichlorophenyl)acetyl-2-(­1-pyrrolidinyl)methylpiperidine hydrochloride

nfarct volume after 3 days of reperfusion in the ipsilateral cortex and CP complex in male rats treated with vehicle saline (n=15) or 1 mg/kg per hour BRL 52537 (n=15) started at onset of reperfusion and continued for 22 hours (male-vehicle n=15; male-BRL n=15; mean±SEM). *P<0.05 vs male vehicle controls. doi: 10.1161/01.STR.0000169928.76321.3d

nfarct volume after 3 days of reperfusion in the ipsilateral cortex and CP complex in male rats treated with vehicle saline (n=15) or 1 mg/kg per hour BRL 52537 (n=15) started at onset of reperfusion and continued for 22 hours (male-vehicle n=15; male-BRL n=15; mean±SEM). *P<0.05 vs male vehicle controls. doi: 10.1161/01.STR.0000169928.76321.3d