CAFs reside within tumor tissue and serve various functions including suppression of immune responses to cancerous cells, support of tumor cell growth and enhancement of metastasis.
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- Sunil Singh. (2021). Engineered Organotypic Breast Tumor Model for Mechanistic Studies of Tumor-Stromal Interactions and Drug Discovery. University of Akron, Doctoral Dissertation
- Luis P. Ferreira, Vitor M. Gaspar, Maria V. Monteiro, Bruno Freitas, Nuno J.O. Silva, and Joao F. Mano. (2020). Screening of Dual Chemo-Photothermal Cellular Nanotherapies in Organotypic Breast Cancer 3D Spheroids. Journal of Controlled Release. doi: 10.1016/j.jconrel.2020.12.054
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