Carcinoma associated fibroblasts (CAFs) have recently been implicated in important aspects of epithelial solid tumor biology such as neoplastic progression, tumor growth, angiogenesis, and metastasis.
Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.
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- Sunil Singh. (2021). Engineered Organotypic Breast Tumor Model for Mechanistic Studies of Tumor-Stromal Interactions and Drug Discovery. University of Akron, Doctoral Dissertation
- Luis P. Ferreira, Vitor M. Gaspar, Maria V. Monteiro, Bruno Freitas, Nuno J.O. Silva, and Joao F. Mano. (2020). Screening of Dual Chemo-Photothermal Cellular Nanotherapies in Organotypic Breast Cancer 3D Spheroids. Journal of Controlled Release. doi: 10.1016/j.jconrel.2020.12.054
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