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Brain-derived Neurotrophic Factor (BDNF) is a member of the NGF family of neurotrophic factors. BDNF, NGF, NT-3, and NT-4/5 are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system. High levels of expression of BDNF have been detected in the hippocampus, cerebellum, fetal eye, and placenta.
Tested by Western blotting internally with recombinant protein and not with native tissues.
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- Karine Bédard, Stéphanie Segura, Stéphanie Mahaut, Catherine Tardivel, Guylaine Ferland, Bruno Lebrun, Pierrette Gaudreau. (2012). Effects of aging and caloric restriction on brainstem satiety center signals in rats. Mechanisms of Ageing and Development. Mechanisms of Ageing and Development, doi: 10.1016/j.mad.2012.01.004
- Leanne M. Ramer, Lowell T. McPhail, Jaimie F. Borisoff, Lesley J. J. Soril, Timothy K. Y. Kaan, Jae H. T. Lee, James W. T. Saunders, Lucy P. R. Hwi, and Matt S. Ramer. (2007). Endogenous TrkB Ligands Suppress Functional Mechanosensory Plasticity in the Deafferented Spinal Cord The Journal of Neuroscience, 27(21):5812-5822. doi: 10.1523/JNEUROSCI.0491-07.2007
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