Human GAP-32 is a 24,672 dalton protein (283 amino acids) expressed in neurons during development and reexpressed during axonal regeneration. It is also known as neuromodulin, calmodulin--binding protein P57, protein F1, and B-50. It is found in neuronal cell bodies, axons, and growth cones.Although its function has long been debated, it seems likely that GAP-43 may act as an osmosensory protein regulating intracellular calcium levels.
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