Product Details
Catalog Number: CH23026
Applications: IHC
Type: Chicken IgY
Immunogen: Synthetic peptide (keyhole limpet hemocyanin -KLH conjugate) corresponding to different regions of the metabotropic glutamate receptor type 5 gene product, but are shared between the human (NP_001137303.1, NCBI) and mouse (Q3UVX5.2, NCBI) sequences.
Storage: Store at 4°C in the dark
Shipping: Ambient
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 2915
UniProt: P41594
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$125.00Add to Cart

Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8

mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

Images
Adult mouse cochlear ganglion stained with mGluR5  (green, CH23026) and  Tuj-1 (red, CH23005) and DAPI (blue).

Adult mouse cochlear ganglion stained with mGluR5 (green) and Tuj-1 (red, CH23005) and DAPI (blue). Protocol on datasheet.

Adult mouse cochlear ganglion stained with mGluR5  (green, CH23026) and  Tuj-1 (red, CH23005) and DAPI (blue).

Adult mouse cochlear ganglion stained with mGluR5 (green) and Tuj-1 (red, CH23005) and DAPI (blue). Protocol on datasheet.