Product Details
Catalog Number: CH23028
Applications: ICC, IHC
Type: Chicken IgY
Immunogen: Peptide corresponded to a region of the synthetic peptide QHF QEK VES LEQ EAA NER QQ, which corresponds to residues #433-452 of the human gene product (NP_000475.1)
Storage: Store at 4°C in the dark
Shipping: Ambient
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 351
UniProt: P05067
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$125.00Add to Cart

Alzheimer's disease, the most common cause of dementia in the elderly, exists in both familial and sporadic forms. Genetic studies have identified three genes; beta-amyloid precursor protein (APP), Presenilin-1 and Presenilin-2 which, when mutated, can cause familial forms of Alzheimer's disease. APP and APP-like proteins are transmembrane glycoproteins with a similar modular domain structure.

Images
Amyloid Precursor Protein, Peptide #3 IHC Image

Mouse cortical neurons in culture; green staining is APP-immunoreactivity using fluorescien-labeled goat anti-chicken IgY (CH23101) and rhodamine-labeled phalloidin as a counterstain.

Amyloid Precursor Protein, Peptide #3 IHC Image

Mouse cortical neurons in culture; green staining is APP-immunoreactivity using fluorescien-labeled goat anti-chicken IgY (CH23101) and rhodamine-labeled phalloidin as a counterstain.