The neurotransmitter gamma-aminobutyric acid (GABA) mediates an inhibitory signal upon binding to two ligand-gated channels, GABA-A and GABA-C receptors, and a G-protein linked receptor, GABA-B.
The GABA-B receptor is a heterodimeric complex composed of two 7-transmembrane GPCRs termed GABA-B R1 and GABA-B R2. GABA-B receptors have been implicated in the GABA-induced modulation of sympathetic and catecholaminergic pathways in the central nervous system.
- Product Reviews
- Product Publications
- Carolina Ladera, María del Carmen Godino, Ricardo Martín, Rafael Luján, Ryuichi Shigemoto, Francisco Ciruela, Magdalena Torres and José Sánchez-Prieto. (2007). The coexistence of multiple receptors in a single nerve terminal provides evidence for pre-synaptic integration. Journal of Neurochemistry, doi: 10.1111/j.1471-4159.2007.04964.x
If you've used this product in a publication, let us know. Email firstname.lastname@example.org, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size GABA A receptor alpha 4 GT41008 100 ug GABA A Receptor beta 3 GT41011 100 ug GABA A Receptor beta 3 MO50001 100 ul GABA A Receptor, delta subunit MO50002 100 ul GABA A receptor, pi subunit RA30047 50 ug GABA B Receptor1 RA20003 100 ul GABA Receptor Associated Protein RA19014 100 ug GAD1/GAD67 GT15142 100 ug GAT-2 RA24459 100 ul