Product Details
Catalog Number: GT15023
Applications: ICC, IHC, E
Type: Goat IgG
Immunogen: Recombinant mouse Agouti-Related Protein
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse, Rat
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$375.00Add to Cart

Agouti-related Protein (AgRP), also known as the protein product of the agouti-related transcript (ART), is a neuropeptide and a functional antagonist of alpha-MSH on MC-3 and MC-4 receptors, both of which are implicated in obesity. AgRP shares sequence and structural homology with the Agouti protein and has similar expression patterns in both mouse and human.

It is also supsected to play a role in modulation of pain.

Images

Double-staining of Fos positive neurons with anti-AgRP in the DMH. Overview of doublestaining with anti-AgRP (A) and anti-Fos (B) in the DMH. Merge image of double-staining showed that Fos-ir positive neurons (green staining) were encircled in a network of AgRP-irpositive fibers (red staining) in the DMH (C). doi: 10.1016/j.brainres.2008.01.054.

Double-staining of Fos positive neurons with anti-AgRP in the DMH. Overview of doublestaining with anti-AgRP (A) and anti-Fos (B) in the DMH. Merge image of double-staining showed that Fos-ir positive neurons (green staining) were encircled in a network of AgRP-irpositive fibers (red staining) in the DMH (C). doi: 10.1016/j.brainres.2008.01.054.