Product Details
Catalog Number: GT15030
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: Recombinant mouse RAGE extracellular domain
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse
Entrez: 177
UniProt: Q15109
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

RAGE (receptor for advanced glycation end products) is a multiligand type I transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily. RAGE ligands include advanced glycation end products (AGEs), amyloid-beta (A beta) peptide, HMG-1 (also known as Amphoterin), and several members of the S100 protein superfamily. RAGE has potential involvement in several pathological processes including diabetes, Alzheimer's disease (AD), systemic amyloidosis, and tumor growth. RAGE may also mediate several physiological functions such as neuronal outgrowth, survival, and regeneration, and play a part in pro-inflammatory reactions.

Images
RAGE staining of  cryostat tissue sections of mouse brain. Sections were stained Rhodamine Red X (red).

RAGE staining of cryostat tissue sections of mouse brain. Sections were stained Rhodamine Red X (red).

RAGE staining of  cryostat tissue sections of mouse brain. Sections were stained Rhodamine Red X (red).

RAGE staining of cryostat tissue sections of mouse brain. Sections were stained Rhodamine Red X (red).