There are at least 20 structurally and functionally related BMPs, which are members of the TGF-beta superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation. They are also involved in embryogenesis and morphogenesis of various tissues and organs. BMPs regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. Similar to other TGF-beta family proteins, BMPs are highly conserved across animal species.
BMP-5 promotes dendritic growth in cultured sympathetic neurons and is inhibited by chordin and noggin. It is expressed in the trabecular meshwork and optic nerve head and may have a role in the development and normal function. It is also expressed in the lung and liver.
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Name Catalog # Size BMP-1/PCP GT15120 100 ug BMP-10 RA30003 100 ug BMP-2 Inducible Kinase (BIKE) RA30004 100 ug BMP-2/4 GT15053 100 ug BMP-3 MO15038 100 ug BMP-3b/GDF-10 GT15166 100 ug BMP-4 MO20038 100 ug BMP-4 RA30035 100 ug BMP-6 GT15167 100 ug BMP-7 MO15079 100 ug BMP-8 GT15161 100 ug Chordin GT15191 100 ug GDF-3 GT15176 100 ug GDF-5 GT15177 100 ug GDF-8/Myostatin GT15213 100 ug GDF-9 GT15214 100 ug RUNX2 GT15188 100 ug