Product Details
Catalog Number: GT15068
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: Recombinant mouse Endostatin
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse
Entrez: 80781
UniProt: P39060
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$345.00Add to Cart
50 ug$190.00Add to Cart

Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis.

Endostatin eliminated tumors in mice. Researchers reported that the proteins eliminated forms of colon, prostate, breast and brain cancers in the animal experiments. Endostatin also appears to block new blood vessel growth in tumors blocking the metastatic process.

Images
Endostatin staining in mouse brain.

Endostatin staining in mouse brain.

Endostatin staining in mouse brain.

Endostatin staining in mouse brain.