Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE.
- Product ReviewsThe antibody worked great in my Western blot. It worked better than the competitors antibody.. Product Name: ADAM10, Goat – (Cat# GT15079) http://bit.ly/1GvNr1b Organization: Virginia Commonwealth UniversityRebecca - Jun 24, 2015 - Rating: 5.0Great ordering experience and antibody came the next day. Product Name: ADAM10, Goat – (Cat# GT15079) http://bit.ly/1GvNr1b Organization: Virginia Commonwealth UniversityRebecca - Jun 19, 2015 - Rating: 5.0
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