Product Details
Catalog Number: GT15079
Applications: WB, IHC
Type: Goat IgG
Dilutions: IHC 1-2 ug/mL; WB 1-2 ug/mL
Immunogen: Recombinant mouse ADAM10 ectodomain
Storage: Antibody can also be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Mouse
Entrez: 102
UniProt: O14672
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE.

Images

Detection of ADAM10 in cryostat sections of mouse brain using goat anti-mouse ADAM10 antibody. Tissues were stained using anti-goat HRP-DAB (brown color) Cell and counterstained with hematoxylin (blue color).

Detection of ADAM10 in cryostat sections of mouse brain using goat anti-mouse ADAM10 antibody. Tissues were stained using anti-goat HRP-DAB (brown color) Cell and counterstained with hematoxylin (blue color).