Product Details
Catalog Number: GT15113
Applications: ICC, WB, IHC, E
Type: Goat IgG
Immunogen: Recombinant mouse TNF alpha
Storage: Antibody can be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse
Entrez: 7124
UniProt: P01375
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

Tumor necrosis factor alpha (TNF-alpha), also called cachectin, is produced by many normal and tumor cells in response to a wide variety of stimuli, including viruses, bacteria, parasites, cytokines and mitogens. In solution, TNF-alpha is a trimeric molecule. Both the transmembrane and the soluble, secreted forms of TNF-alpha are biologically active. TNF-alpha is an extremely pleiotropic cytokine due to the ubiquity of its receptors, to its ability to activate multiple signal transduction pathways and its ability to induce or suppress the expression of a wide number of genes.

Images
TNF-alpha staining of  immersion fixed activated mouse T Cells at 15 µg/mL for 3 hours at room temperature (red) and counterstained (green).

TNF-alpha staining of immersion fixed activated mouse T Cells at 15 µg/mL for 3 hours at room temperature (red) and counterstained (green).

TNF-alpha staining of  immersion fixed activated mouse T Cells at 15 µg/mL for 3 hours at room temperature (red) and counterstained (green).

TNF-alpha staining of immersion fixed activated mouse T Cells at 15 µg/mL for 3 hours at room temperature (red) and counterstained (green).