Product Details
Catalog Number: GT15170
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: Purified, NS0-derived, recombinant human LINGO-1 (rhLINGO-1; aa 40 - 556; Accession # AAH11057).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 84894
UniProt: Q96FE5
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

LINGO-1 (Leucine-rich repeat- and Ig domain-containing nogo receptor-interacting protein 1) is a transmembrane protein of the leucine-rich repeat (LRR) family, ribonuclease inhibitor subfamily. The four known LINGO proteins contain LRR and IgCAM domains in the extracellular portion and share 44-61% aa identity. LINGO-1 is restricted to the nervous system and is concentrated in the brain as a component of the NgR1/p75 and NgR1/Taj (Troy) signaling complexes. LINGO-1 negatively regulates neurite outgrowth and myelination, and is highly conserved, showing 99% aa identity between human, mouse and rat.

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