Product Details
Catalog Number: GT15181
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: Purified, insect cell line Sf 21-derived, recombinant human platelet-derived endothelial cell growth factor (rhPD-ECGF).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 1890
UniProt: P19971
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

Platelet-Derived Endothelial Cell Growth Factor is also named thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is identified as an angiogenic factor.

PD-ECGF might contribute to the growth of uterine cervical and prostate cancer (via angiogenesis related to vascular spreading) and a variety of other malignancies.  

Images
PD-ECGF staining of paraffin-embedded human prostate cancer tissue sections. Tissue was stained  using  Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

PD-ECGF staining of paraffin-embedded human prostate cancer tissue sections. Tissue was stained using Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

PD-ECGF staining of paraffin-embedded human prostate cancer tissue sections. Tissue was stained  using  Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

PD-ECGF staining of paraffin-embedded human prostate cancer tissue sections. Tissue was stained using Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).