Product Details
Catalog Number: GT15196
Applications: IHC
Type: Goat IgG
Immunogen: Purified, E. coli-derived, recombinant human Bcl-w (rhBcl-w).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 599
UniProt: Q92843
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

Bcl-w is a pro-survival (anti-apoptotic) member of the Bcl-2 family; a family involved in the regulation of cellular apoptosis at the mitochondrion. Relative to its Bcl-2 counterparts there is considerably less data on this prticular protein. 

Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.

Images
Bcl-w staining of  paraffin-embedded human spleen tissue sections. Tissues were stained using  HRP-DAB (brown) and counterstained with hematoxylin (blue).

Bcl-w staining of paraffin-embedded human spleen tissue sections. Tissues were stained using HRP-DAB (brown) and counterstained with hematoxylin (blue).

Bcl-w staining of  paraffin-embedded human spleen tissue sections. Tissues were stained using  HRP-DAB (brown) and counterstained with hematoxylin (blue).

Bcl-w staining of paraffin-embedded human spleen tissue sections. Tissues were stained using HRP-DAB (brown) and counterstained with hematoxylin (blue).