The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate.
SOX9 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX9 is expressed in mesenchymal progenitors that give rise to chondrocytes and osteoblasts. It is also expressed in the central nervous system, neural crest, intestine, pancreas and testis. Mutations in SOX9 are associated with defects in sex determination, cartilage and bone development, as well as abnormalities of the heart, kidneys, brain, gut and pancreas.
Note: This antibody has been selected for its ability to recognize human SOX9 in IHC, direct ELISAs and western blots, this antibody shows approximately 10% cross-reactivity with rhSOX10 and less than 5% cross-reactivity with rhSOX2, rhSOX3, rhSOX7 and rhSOX17.
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Name Catalog # Size SOX-10 MO47006 100 ug SOX-2/SRY (sex determining region Y)-box 2 MO47038 100 ul SOX1 GT15208 100 ug SOX10 GT15218 100 ug. SOX10 MO15116 100 ug SOX17 GT15094 100 ug SOX2 GT15098 100 ug. SOX2 MO15040 100 ug SOX2 RA25021 100 ul SOX21 GT15209 100 ug SOX3 GT15119 100 ug SOX6 RA19023 100 ug SOX7 MO15050 100 ug SOX7 MO15050 50 ug SRY (Sex Determining Region Y)-Box 11/SOX-11 MO47052 100 ul