Product Details
Catalog Number: GT15212
Applications: IHC, E, FC
Type: Sheep IgG
Immunogen: NS0-derived, recombinant mouse Repulsive Guidance Molecule B.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse
Entrez: 285704
UniProt: Q6NW40
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

The Repulsive Guidance Molecule (RGM) family of proteins function as BMP co-receptors. Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.

Images
RGM-B staining of cryostat section of mouse brain (trigeminal ganglia).Tissue was stained with HRP-DAB and counterstained with hematoxylin (blue).

RGM-B staining of cryostat section of mouse brain (trigeminal ganglia).Tissue was stained with HRP-DAB and counterstained with hematoxylin (blue).

RGM-B staining of cryostat section of mouse brain (trigeminal ganglia).Tissue was stained with HRP-DAB and counterstained with hematoxylin (blue).

RGM-B staining of cryostat section of mouse brain (trigeminal ganglia).Tissue was stained with HRP-DAB and counterstained with hematoxylin (blue).