Product Details
Catalog Number: GT15226
Applications: WB, IHC, E, NB
Type: Goat IgG
Immunogen: Purified, CHO cell-derived, recombinant human Fas Ligand (rhFas Ligand).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 356
UniProt: P48023
Downloads: Datasheet (pdf)
Product Sizes
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50 ug$365.00Add to Cart

FAS Ligand,  also known as CD95L or APT1LG1 , is a member of the TNF receptor family.

The full length Fas-L protein has a cytoplasmic domain, transmembrane (Type II) domain and extracellular domain. The membrane-bound form of Fas-L is proteolytically cleaved to produce soluble Fas-L. There are at least 2 known isoforms of Fas-L produced by alternate splicing. 

Fas ligand-receptor interactions play an important role in the regulation of the immune system and the progression of cancer.

Images

Figure 1-The biological activity of rhFas Ligand was measured by its ability to induce apoptosis of Jurkat cells (Cifone M.G. et al., 1994, J. Exp. Med. 180:1547). Figure 2-To measure the ability of the antibody to neutralize the bioactivity of rhFas Ligand.

Figure 1-The biological activity of rhFas Ligand was measured by its ability to induce apoptosis of Jurkat cells (Cifone M.G. et al., 1994, J. Exp. Med. 180:1547). Figure 2-To measure the ability of the antibody to neutralize the bioactivity of rhFas Ligand.