Product Details
Catalog Number: GT15241
Applications: ICC, WB
Type: Sheep IgG
Immunogen: E. coli derived recombinant human ZIC3. His380-Val467 Accession # O60481.
Storage: Antibody can also be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 7547
UniProt: O60481
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

ZIC3 or zinc finger protein of the cerebellum 3 is a 50 kDa (predicted) member of the GLI C2H2type Zn finger protein family. It is involved in the maintenance of pluripotency in ES cells by preventing endodermal lineage specification in embryonic stem cells. The protein is also expressed in the cerebellum.

Defects in ZIC3 are the cause of visceral heterotaxy X-linked type 1 (HTX1). A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects.