Product Details
Catalog Number: GT15244
Applications: ICC, WB
Type: Goat IgG
Immunogen: E. coli-derived recombinant human Brg1. Gln673-Asn774
Storage: Antibody can also be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 6597
UniProt: P51532
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

Brg1, also known as ATP-dependent helicase SMARCA4, is a  member of the SNF2 helicase family of molecules. It may facilitate and inhibit gene transcription. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin.  Brg1 works to activate or repress transcription.  It is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells

It is also thought to be crucial to the development of sperm and smooth muscle in the gastrointestinal tract.