Product Details
Catalog Number: GT15250
Applications: ICC, WB, FC
Type: Goat IgG
Dilutions: Western Blot: 0.25 ug/ml Flow Cytometry: 2.5 ug/10^6 Cells Immunocytochemistry: 5-15 ug/ml
Immunogen: Mouse myeloma cell line NS0-derived recombinant human VE-Cadherin Asp48-Gln593
Storage: Antibody can also be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Species Reactivity: Human
Entrez: 1003
UniProt: P33151
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$529.00Add to Cart

Vascular endothelial-cadherin (VE-CAD), also called 7B4 and cadherin-5, is a member of the cadherin family of cell adhesion molecules. Cadherins are calcium‑dependent transmembrane proteins which bind to one another in a homophilic manner. On their cytoplasmic side, they associate with the three catenins, alpha, beta, and gamma (plakoglobin). Cadherins play a role in development, specifically in tissue formation. They may also help to maintain tissue architecture in the adult. VE-Cadherin has been shown to play important roles in vasculogenesis and angiogenesis.

Images
Immunocytochemistry

Immunocytochemistry: VE‑Cadherin was detected in immersion fixed HUVEC human umbilical vein endothelial cells using Goat Anti-Human VE‑Cadherin Antigen Affinity-purified Polyclonal Antibody (GT15250) at 10 µg/mL for 3 hours at room temperature.

Immunocytochemistry

Immunocytochemistry: VE‑Cadherin was detected in immersion fixed HUVEC human umbilical vein endothelial cells using Goat Anti-Human VE‑Cadherin Antigen Affinity-purified Polyclonal Antibody (GT15250) at 10 µg/mL for 3 hours at room temperature.

Western Blot

Western blot shows lysate of HUVEC human umbilical vein endothelial cells. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Human VE‑Cadherin Antigen Affinity-purified Polyclonal Antibody. A specific band was detected for VE‑Cadherin at approximately 125 kDa (as indicated).

Western Blot

Western blot shows lysate of HUVEC human umbilical vein endothelial cells. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Human VE‑Cadherin Antigen Affinity-purified Polyclonal Antibody. A specific band was detected for VE‑Cadherin at approximately 125 kDa (as indicated).