Resveratrol is a naturally occurring phenolic antioxidant that has antitumor and antiplatelet effects (1). It stimulates SIRT1 and increases longevity in yeast (2). Resveratrol ameliorates ageing-related phenotypes by inhibition of cAMP phosphodiesterases (3).
1) Fremont (2000), Biological effects of resveratrol; Life Sci., 66 663
2) Howitz et al. (2003), Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan; Nature, 425 191
3) Park et al. (2012), Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases; Cell, 148 421
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