The biological activities of the neurotrophins are mediated by binding to the different members of the Trk family tyrosine kinase receptors. Three Trk family proteins, TrkA, TrkB and TrkC, exhibiting different ligand specificities, have been identified. At the protein sequence level, Trks are highly conserved between species and the proteins exhibit cross-species activity.
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- Hui-Juan Yang, Hui-Juan Yang, Xiao-Yan Yang, Hui-Juan Yang, Xiao-Yan Yang, Ying-Chun Ba, Jiang-Xia Pang, Bu-Liang Meng2, Na Lin, Li-Yan Li, Xin-Yi Dong, Yu Zhao, Chang-Fu Tian and Ting-Hua Wang. (2009). Role of Neurotrophin 3 in spinal neuroplasticity in rats subjected to cord transection. Growth Factors, Vol. 27, No. 4, Pages 237-246. doi: 10.1080/08977190903024298
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