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Nestin is a protein expressed in neural crest cells, CNS neural stems cells, as well as a few non-neural cell types in the embryo, including cells within the pancreatic islets of Langerhans and the limb bud. Nestin is an intermediate filament-associated protein, and contributes to the cytoskeleton. |
- Product ReviewsI recommend this product Product Name: Nestin – (Cat# MO15012) Organization: Georgia State UniversityJie Xu - Jan 11, 2013 - Rating: 5.0
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- Product Publications
Product Publications
- Vivian W. Lau Simon R. Platt Harrison E. Grace Emily W. Baker Franklin D. West. (2018). Human iNPC therapy leads to improvement in functional neurologic outcomes in a pig ischemic stroke model. Brain and Behavior. 18 April 2018 https://doi.org/10.1002/brb3.972
- Aldo Pourchet, Aram S. Modrek, Dimitris G. Placantonakis, Ian Mohr and Angus C. Wilson. (2017). Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons. Pathogens, 6(2), 24; doi: 10.3390/pathogens6020024
- Reuven Edri, Yakey Yaffe, Michael J. Ziller, Naresh Mutukula, Rotem Volkman, Eyal David, Jasmine Jacob-Hirsch, Hagar Malcov, Carmit Levy, Gideon Rechavi, Irit Gat-Viks, Alexander Meissner & Yechiel Elkabetz. (2015). Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors. Nature Communications 6, Article number: 6500. doi: 10.1038/ncomms7500
- N. L. Boyd, S. K. Dhara, R. Rekaya, E. A. Godbey, K. Hasneen, R. R. Rao, F. D. West III, B. A. Gerwe, S. L. Stice. (2007). BMP4 Promotes Formation of Primitive Vascular Networks in Human Embryonic Stem Cell–Derived Embryoid Bodies. Exp Biol Med, vol. 232 no. 6 833-843.
- J. Simon Lunn, Crystal Pacut, Emily Stern, Stacey A. Sakowski, J. Matthew Velke, Sue O'Shea, Eva L. Feldman. (2012). Intraspinal transplantation of neurogenin-expressing stem cells generates spinal cord neural progenitors. Neurobiology of Disease, Volume 46, Issue 1, April 2012, Pages 59–68. doi: 10.1016/j.nbd.2011.12.044
- A. Young, D.W. Machacek, S.K. Dhara, P.R. MacLeish, M. Benveniste, M.C. Dodla, C.D. Sturkie and S.L. Stice. (2011). Ion channels and ionotrophic receptors in a human embryonic stem cell derived neural progenitors. Neuroscience, doi: 10.1016/j.neuroscience.2011.04.039
- Mariano Guardia Clausi, Laura A Pasquini, Eduardo F Soto and Juana M Pasquini. (2010). Apotransferrin-induced recovery after hypoxic/ischaemic injury on myelination. ASN NEURO, 2(5):art:e00048. doi: 10.1042/AN20100020
- Sujoy K. Dhara, Kowser Hasneen, David W. Machacek, Nolan L. Boyd, Raj R. Rao, Steven L. Stice. (2008). Human neural progenitor cells derived from embryonic stem cells in feeder-free cultures. Differentiation, 76 (5) , 454–464. doi: 10.1111/j.1432-0436.2007.00256.x
Product Patent Application
- Shuibing Chen, Ting Zhou, Lei Tan, and Qishengin Zhang. (2020). Compounds and Compositions for Inhibition and Elimination of Zika Infection and Uses for Same. United States Patent Application 20200102320
- Lorenz Studer and Jason Tchieu. (2020). Stem Cell-Derived Astrocytes, Methods of Making and Methods of Use. United States Patent Application 20200024574
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- Related Products
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Name Catalog # Size α-Internexin/NF 66 MO22102 100ul α-Internexin/NF 66 MO22154 100 ul AP-2 Alpha RA18023 100 ul ATPase Na+/K+ transporting alpha 1 MO25023 50 ul Doublecortin/DCX MO22113 100 ul GAP43 MO22118 100 ul GAP43 MO22170 100 µl GAP43 RA25086 100 ul GAP43 (IgG) MO22171 100 µl Laminin RA25038 100 ul Laminin 111 RA22121 100 ul MSX1/HOX7 GT41015 100 ug Musashi-1 RA14128 50 ul Nestin CH22123 100 ul Nestin MO22183 100 ug Nestin RA22125 100 ul Netrin-4 (NTN4) RA21023 50 ug Neurofilament alpha-internexin/NF66 CH22101 100 ul Neurofilament alpha-internexin/NF66 MO25017 500 ul Neurofilament alpha-internexin/NF66 RA22102 100 ul Notch1 RA19069 100 ul Notch3 RA19070 100 ug PAX-8 MO47029 100 ul PAX3 GT41025 100 ug Podoplanin MO47016 100 ul S-100 MO47059 100 ul SOX-2/SRY (sex determining region Y)-box 2 MO47038 100 ul SOX2 RA25021 100 ul SRY (Sex Determining Region Y)-Box 11/SOX-11 MO47052 100 ul Vimentin CH22108 100 ul Vimentin GT22103 100 ul Vimentin MO22115 100 ul Vimentin RA22124 100 ul of Serum
Images
Nestin staining of human glioblastoma cells.
Nestin staining of human glioblastoma cells.
Nestin staining of human neural progenitor cells grafted into the rat brain, 24 weeks post-op. One is of processes running along the host corpus callosum, one of cells in the hippocampus, weakly counterstained with human nuclear antigen (brown). Nestin concentration was 1:1000, overnight at room temp, visualised using the DAKO vector SG kit. Courtesy of Dr. Rike Zietlow, Cardiff University
Nestin staining of human neural progenitor cells grafted into the rat brain, 24 weeks post-op. One is of processes running along the host corpus callosum, one of cells in the hippocampus, weakly counterstained with human nuclear antigen (brown). Nestin concentration was 1:1000, overnight at room temp, visualised using the DAKO vector SG kit. Courtesy of Dr. Rike Zietlow, Cardiff University
Nestin staining of human week-11 fetal neural progenitor cells. Cells were stained using goat anti-mouse Alexa Fluor 488 secondary antibody (green) (Molecular Probe, A-11001) and counterstained with DAPI (blue).
Nestin staining of human week-11 fetal neural progenitor cells. Cells were stained using goat anti-mouse Alexa Fluor 488 secondary antibody (green) (Molecular Probe, A-11001) and counterstained with DAPI (blue).
Immunostaining of hNP1 Progenitors before and after differentiation. The culture was highly homogenous with neural rosettes. Differentiation (2007) DOI: 10.1111/j.1432-0436.2007.00256.x
Immunostaining of hNP1 Progenitors before and after differentiation. The culture was highly homogenous with neural rosettes. Differentiation (2007) DOI: 10.1111/j.1432-0436.2007.00256.x
Accurate detection of intracellular antigens with optimized fixation-permeabilization conditions preserving surface antigens. Flow cytometric detection of TUJ1, MAP2 and nestin antigens in BJ fibroblasts and the neural SH-SY5Y cell line. doi:10.1371/journal.pone.0068519.g003
Accurate detection of intracellular antigens with optimized fixation-permeabilization conditions preserving surface antigens. Flow cytometric detection of TUJ1, MAP2 and nestin antigens in BJ fibroblasts and the neural SH-SY5Y cell line. doi:10.1371/journal.pone.0068519.g003