FosB is one of four Fos family proteins that associate withJun family proteins to form the AP-1 transcription factor complex. AP-1 activity is important for gene transcription in a wide variety of cellular processes.
Cancer: Strong differences in the expression pattern of AP-1 family members are present in breast tumors, and that certain members of this family, such as FosB might be involved in the pathogenesis of these tumors.
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