Product Details
Catalog Number: MO15055
Applications: WB
Type: Mouse IgG
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a rat immunized with purified bovine brain Calcineurin holoenzyme containing both the A and B subunits.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 5530
UniProt: Q08209
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$255.00Add to Cart

Calcineurin A, also known as PP2B and PPP3CA, is the 59 kDa catalytic subunit of the calcium/calmodulin-dependent protein phosphatase. When activated by calcium in the presence of the regulatory B subunit and calmodulin, Calcineurin A selectively removes phosphates from serine and threonine residues on target proteins. Although ubiquitously expressed, Calcineurin levels are highest in the brain, where the phosphatase plays a role in the formation and retention of memories.

Images

Recombinant human Calcineurin A (1 ng) and lysates prepared from human HT29, mouse TS1, and rat Nb2-11 cells were resolved by SDS-PAGE, transferred to an Immobilon-P membrane, and immunoblotted with 1 μg/mL anti-Calcineurin A, as described on datasheet. A ten second exposure to film is shown.

Recombinant human Calcineurin A (1 ng) and lysates prepared from human HT29, mouse TS1, and rat Nb2-11 cells were resolved by SDS-PAGE, transferred to an Immobilon-P membrane, and immunoblotted with 1 μg/mL anti-Calcineurin A, as described on datasheet. A ten second exposure to film is shown.