Product Details
Catalog Number: MO15070
Applications: WB, IHC
Type: Mouse IgG
Immunogen: insect cell line Sf 21-derived, recombinant human interleukin 2 soluble receptor alpha (rhIL-2 sRAlpha).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein A purified
Format B: Ascites Fluid
Species Reactivity: Human
Entrez: 3559
UniProt: P01589
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$155.00Add to Cart

Human IL-2 R alpha, also known as Tac antigen and as CD25, is a 272 amino acid (aa) precursor type I membrane protein with a 21 aa signal peptide, a 219 aa extracellular region, a 19 aa transmembrane region, and a 13 aa cytoplasmic domain. By itself, IL 2 R alpha binds IL-2 with low affinity. However, when IL-2 R alpha is associated with IL-2 R beta and the common gamma chain, a high affinity heterotrimeric receptor complex that transduces IL-2 signals is formed.

Images
IL-2 Rα staining of frozen tissue sections of human lymph node. Tissue sections were stained using anti-mouse ABC-HRP, NovaRed (red) substrate and Haematoxylin (blue) counterstain.

IL-2 Rα staining of frozen tissue sections of human lymph node. Tissue sections were stained using anti-mouse ABC-HRP, NovaRed (red) substrate and Haematoxylin (blue) counterstain.

IL-2 Rα staining of frozen tissue sections of human lymph node. Tissue sections were stained using anti-mouse ABC-HRP, NovaRed (red) substrate and Haematoxylin (blue) counterstain.

IL-2 Rα staining of frozen tissue sections of human lymph node. Tissue sections were stained using anti-mouse ABC-HRP, NovaRed (red) substrate and Haematoxylin (blue) counterstain.