Product Details
Catalog Number: MO15075
Applications: WB, IHC
Type: Mouse IgG
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human Insulin-like Growth Factor Binding Protein 3 (rhIGFBP-3).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Entrez: 3486
UniProt: P17936
Downloads: Datasheet (pdf)
Product Sizes
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500ug$325.00Add to Cart

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.

Images
IGFBP-3 staining of Paraffin-embedded tissue. Sections of human placenta were stained using anti-mouse ABC-HRP, AEC (red) substrate and Haematoxylin (blue).

IGFBP-3 staining of Paraffin-embedded tissue. Sections of human placenta were stained using anti-mouse ABC-HRP, AEC (red) substrate and Haematoxylin (blue).

IGFBP-3 staining of Paraffin-embedded tissue. Sections of human placenta were stained using anti-mouse ABC-HRP, AEC (red) substrate and Haematoxylin (blue).

IGFBP-3 staining of Paraffin-embedded tissue. Sections of human placenta were stained using anti-mouse ABC-HRP, AEC (red) substrate and Haematoxylin (blue).