"We recently ordered your BMP7 antibody, and I used it on rat spinal cord sections. It worked beautifully." Molly Fuller (Dr. Robert Miller Lab), Case Western University.
BMP-7, or osteogenic protein 1 (OP-1), is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor β (TGF-β) superfamily. BMPs regulate cartilage and bone formation, embryogenesis and morphogenesis of various tissues and organs, and growth, differentiation, chemotaxis and apoptosis of various cell types. Biologically active BMP-7 is a disulfide-linked homodimer. Cellular responses to BMP-7 have been shown to be mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors.
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- Molly L. Fuller, Anne K. DeChant, MS, Brian Rothstein, Andrew Caprariello, Rae Wang, Alison K. Hall, PhD, Robert H. Miller, PhD. (2007). Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions. Annals of Neurology, Volume 62, Issue 3 , Pages 288 - 300. doi: 10.1002/ana.21179
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Name Catalog # Size BMP-1/PCP GT15120 100 ug BMP-10 RA30003 50 ug BMP-2 Inducible Kinase (BIKE) RA30004 50 ug BMP-2/4 GT15053 100 ug BMP-3 MO15038 500 ug BMP-3b/GDF-10 GT15166 100 ug BMP-4 MO15134 100 ug BMP-4 RA30035 50 ug BMP-5 GT15054 100 ug BMP-6 GT15167 100 ug BMP-8 GT15161 100 ug Chordin GT15191 100 ug Chordin-Like 2/CHRDL2 MO15143 100 ug GDF-3 GT15176 100 ug GDF-5 GT15177 100 ug GDF-8/Myostatin GT15213 100 ug GDF-9 GT15214 100 ug RUNX2 GT15188 100 ug