Product Details
Catalog Number: MO15091
Applications: WB, E
Type: Mouse IgG
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a rat immunized with purified, NS0-derived, recombinant mouse Insulin-like Growth Factor Binding Protein 5 (rmIGFBP-5).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Mouse
Entrez: 3488
UniProt: P24593
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$155.00$89.00Add to Cart
500 ug$325.00Add to Cart

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.

IGBP-5 is important to development. It could play a role in certain development related disorders like myotonic dystrophy-1 and cancers.

Images
IGFBP5 staining of paraffin-embedded human liver tissue sections.  Tissues were stained using anti-goat HRP-DAB Cell and Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).

IGFBP5 staining of paraffin-embedded human liver tissue sections. Tissues were stained using anti-goat HRP-DAB Cell and Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).

IGFBP5 staining of paraffin-embedded human liver tissue sections.  Tissues were stained using anti-goat HRP-DAB Cell and Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).

IGFBP5 staining of paraffin-embedded human liver tissue sections. Tissues were stained using anti-goat HRP-DAB Cell and Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).