Product Details
Catalog Number: MO15094
Applications: IHC, E
Type: Mouse IgG
Immunogen: RPKPQQFFGLM
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 6863
UniProt: P20366
Downloads: Datasheet (pdf)
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NameCatalog #
Substance PGP14103
Substance PRA20064
Substance P-PureGP14110

Substance P is a neuropeptide derived from preprotachinin. Substance P is widely distributed in the central and peripheral nervous system. In sensory ganglia, it is expressed by small sensory neurons and is transported to their central and peripheral terminals. The role of substance P in sensory transmission has been studied extensively, and its involvement in nociception and chronic pain is well established. Our guinea pig anti-substance P antibody provides an excellent tool for multicolor immunofluorescence experiments.

Images

Double immunofluorescence staining for GluR5 (red) and SP in sections of L4 DRG. The colocalization is represented in yellow; example of double-stained neurons are indicated with arrow. DRG neurons tallied in five sections from three ganglia in three rats for every double immunostaining.

Double immunofluorescence staining for GluR5 (red) and SP in sections of L4 DRG. The colocalization is represented in yellow; example of double-stained neurons are indicated with arrow. DRG neurons tallied in five sections from three ganglia in three rats for every double immunostaining.

Detection of Substance P in mouse spinal cord (red fluorescence). Tissue was counterstained with Fluoro Nissl Green (green fluorescence)

Detection of Substance P in mouse spinal cord (red fluorescence). Tissue was counterstained with Fluoro Nissl Green (green fluorescence)

Detection of Substance P in mouse spinal cord (red fluorescence). Tissue was counterstained with Fluoro Nissl Green (green fluorescence)

Detection of Substance P in mouse spinal cord (red fluorescence). Tissue was counterstained with Fluoro Nissl Green (green fluorescence)