Product Details
Catalog Number: MO15097
Applications: WB, IHC, E
Type: Mouse IgG
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, E. coli-derived, recombinant human Calbindin D (rhCalbindin D; aa 1 - 261; Accession # P05937).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human, Rat
Entrez: 795
UniProt: P29377
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$275.00Add to Cart

Calbindin-D, also known as Calbindin 1, is a Vitamin D-dependent cytoplasmic protein in the EF-hand calcium binding protein family that includes calmodulin, parvalbumin, troponin C, and S100. Calbindin-D is widely expressed and regulates calcium homeostasis. Calbindin-D protects neurons from excitotoxic and apoptotic cell death by buffering excess calcium. Human, mouse, and rat Calbindin-D share 99% amino acid sequence identity.

Images

Calbindin D staining of paraffin-embedded human cerebellum and frozen rat hypothalamus sections using 25 µg/mL mouse anti-human Calbindin D monoclonal antibody. Tissues were stained using anti-mouse HRP-DAB ( brown) and counterstained with hematoxylin (blue).

Calbindin D staining of paraffin-embedded human cerebellum and frozen rat hypothalamus sections using 25 µg/mL mouse anti-human Calbindin D monoclonal antibody. Tissues were stained using anti-mouse HRP-DAB ( brown) and counterstained with hematoxylin (blue).

Calbindin D staining of paraffin-embedded rat brainstem medulla. Staining is shown in the medial vestibular nucleus using 25 µg/mL mouse anti-human Calbindin D monoclonal antibody. Tissue was stained anti-mouse HRP-AEC and counterstained with hematoxylin (blue).

Calbindin D staining of paraffin-embedded rat brainstem medulla. Staining is shown in the medial vestibular nucleus using 25 µg/mL mouse anti-human Calbindin D monoclonal antibody. Tissue was stained anti-mouse HRP-AEC and counterstained with hematoxylin (blue).