Product Details
Catalog Number: MO15099
Applications: WB, IHC, IP
Type: Mouse IgG
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with rat brain synaptic plasma membranes.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat, Chicken
Entrez: 6857
UniProt: P21579
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$255.00Add to Cart

The Synaptotagmins are a family of integral membrane proteins of synaptic vesicles. Rat Synaptotagmin-1 (Accession # P21707) is a 57 kDa, 421 aa glycoprotein containing two C2 domains related to protein kinase C and sites for palmitoylation and binding of acidic phospholipids, calcium and calmodulin. Synaptotagmin-1 participates in the process of vesicular trafficking and exocytosis by inducing local Ca2+-dependent buckling of the plasma membrane. Rat Synaptotagmin-1 shares 98% aa identity or greater with mouse, human and bovine Synaptotagmin-1.

Images
Synaptotagmin staining of  perfusion fixed frozen sections of rat spinal cord- µg/mL overnight at 4 °C. Tissue was stained (red) and counterstained (green).

Synaptotagmin staining of perfusion fixed frozen sections of rat spinal cord- µg/mL overnight at 4 °C. Tissue was stained (red) and counterstained (green).

Synaptotagmin staining of  perfusion fixed frozen sections of rat spinal cord- µg/mL overnight at 4 °C. Tissue was stained (red) and counterstained (green).

Synaptotagmin staining of perfusion fixed frozen sections of rat spinal cord- µg/mL overnight at 4 °C. Tissue was stained (red) and counterstained (green).