Dopa decarboxylase (DDC), also known as AADC, is a homodimeric vitamin B6-dependent enzyme that catalyzes the decarboxylation of hydroxylated aromatic amino acids (Accession # P20711). DDC is expressed in the adrenal medulla and catecholaminergic neurons. It catalyzes the final step in the synthesis of the neurotransmitters dopamine and serotonin. Defects in DDC are associated with the development of schizophrenia, Parkinson's disease, and hypertension. Human DDC shares 89% aa sequence identity with mouse and rat DDC.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size DOPA decarboxylase RA25065 100 ul Dopamine beta-Hydroxylase RA24600 100 ul phospho-Tyrosine Hydroxylase (Ser40) RA18026 100 ul Tyrosine Hydroxylase CH22122 100 ul Tyrosine Hydroxylase CH23006 100 ul Tyrosine Hydroxylase MO20001 100 ul Tyrosine Hydroxylase MO22186 100 ul Tyrosine Hydroxylase MO22941 100 ul Tyrosine Hydroxylase RA21030 50 ug Tyrosine Hydroxylase RA22135 100 ul Tyrosine Hydroxylase SO25000 100 ul