Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.
These SST Receptors function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone as well as cell growth induced by neuronal excitation in both the central and peripheral nervous systems.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size Alpha 2a Adrenergic Receptor RA14110 150 ul Alpha 2a Adrenergic Receptor RA14110 50 ul Alpha 2c Adrenergic Receptor RA19064 150 ul Alpha 2c Adrenergic Receptor RA19064 50 ul Bradykinin Receptor B2 RA14137 100 ul Corticotropin Releasing Hormone Receptor 1 GT41006 100 ug Frizzled 4/CD344 GT15217 100 ug Frizzled 7 RA30031 50 ug Frizzled 9 RA30032 50 ug GPR12 RA30050 50 ug GPR3 RA30048 50 ug GPR49 RA25071 100 ul GPRC6A RA30049 50 ug Oxytocin RA24604 100 ul Rhodopsin (A531) MO22128 100 ul Rhodopsin (B630) MO22127 100 ul Somatostatin Receptor-1-SSTR1 RA25004 100 ul Somatostatin Receptor-2-SSTR2 RA25005 100 ul Vasopressin V1B Receptor GT41005 100 ug Vasopressin V1B Receptor GT41021 100 ug