Product Details
Catalog Number: MO15116
Applications: ICC, IHC
Type: Mouse IgG
Immunogen: E. coli-derived, recombinant rat SRY (sex determining region Y) box 10 (rrSOX10). Clone: 20B7
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human, Rat
Entrez: 6663
UniProt: P56693
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$295.00Add to Cart

SOX10 is a member of the SRY-related HMG-box family of transcription factors. It is required for the terminal differentiation of oligodendrocytes and myelination. In the peripheral nervous system, SOX10 maintains pluripotency of neural crest stem cells and suppresses neuronal differentiation.

The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Note: This antibody was selected for its ability to detect rat SOX10 in immunohistochemistry experiments. Epitope-mapping experiments indicated that clone 20B7 recognizes a determinant in the first 65 amino acids, which contains sequences unique to SOX101.


1. Lo, L. et al., 2002, Development 129:1553 - 1567.



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