Martilin-1, also named MATN1, Cartilage Matris Protein or CMP, is mainly expressed in cartilage.
Defects in Matrilin-1 lead to cartilage related diseases such as Adolescent idiopathic scoliosis (IS), early onset osteoarthritis.and Relapsing Polychondritis which is an autoimmune disease that affects cartilage in the ear, nose, and respiratory tract.
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