Product Details
Catalog Number: MO15135
Applications: WB
Type: Rat IgG
Dilutions: Western Blot: 1 ug/ml
Immunogen: E. coli-derived recombinant mouse Desert Hedgehog/Dhh Cys23-Gly396
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein A purified
Format B: liquid
Species Reactivity: Mouse
Entrez: 50846
UniProt: O43323
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
500 ug$429.00Add to Cart

Desert Hedgehog (Dhh) belongs to the highly conserved Hedgehog family of proteins which are involved in multiple developmental processes. Hedgehogs are synthesized as 45 kDa precursors that are cleaved autocatalytically. The 19 kDa Nterminal fragment remains membrane associated due to its cholesterol and palmitate modifications. Binding of this fragment to Patched receptors results in the loss of Patched repression of Smoothened signaling. Dhh binds both Patched and Patched 2 as well as Hedgehog interacting protein (Hip).

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