Product Details
Catalog Number: MO15137
Applications: WB
Type: Mouse IgG
Dilutions: Western Blot: 1 ug/ml
Immunogen: E. coli-derived recombinant human Caspase-8 aa 234-391
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein A purified
Format B: liquid
Species Reactivity: Human
Entrez: 841
UniProt: Q14790
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$319.00Add to Cart

Caspase-8 (Cysteine-aspartic acid protease 8/Casp8; also MCH5 and FLICA) is a 28 kDa member of the peptidase C14A family of enzymes. It is known as the initiating caspase for the apoptotic cascade. Caspase-8 acts on procaspases-3, 4, 6, 7, 9 and 10, in addition to c-FLIPL and procaspase-8 itself.

Images
Western Blot

Western blot shows lysates of Jurkat human acute T cell leukemia cell line untreated (-) or treated (+) with Human FAS Antigen Affinity-purified Polyclonal Antibody for indicated times. PVDF membrane was probed with 1 µg/mL of Human Caspase‑8 Monoclonal Antibody, followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody. Specific bands were detected for Caspase‑8 at approximately 55 and 42 kDa (as indicated).

Western Blot

Western blot shows lysates of Jurkat human acute T cell leukemia cell line untreated (-) or treated (+) with Human FAS Antigen Affinity-purified Polyclonal Antibody for indicated times. PVDF membrane was probed with 1 µg/mL of Human Caspase‑8 Monoclonal Antibody, followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody. Specific bands were detected for Caspase‑8 at approximately 55 and 42 kDa (as indicated).