Product Details
Catalog Number: MO15139
Applications: IHC
Type: Mouse IgG
Dilutions: Immunohistochemistry: 8-25 ug/ml
Immunogen: E. coli-derived recombinant human CTGF Glu247-Ala349
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein A purified
Format B: liquid
Species Reactivity: Human
Entrez: 1490
UniProt: P29279
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$339.00Add to Cart

CTGF belongs to the CCN (CYR61/CTGF/NOV) family of secreted proteins that share a common multimodular organization. Each protein contains IGF-binding protein domain, a von Willebrand factor type C domain, a thrombospondin type I domain, and a cysteine knot domain. The multimodular CTGF has the ability to bind multiple ligands and has numerous effects on development, differentation, and disease. The C-terminal cysteine knot motif contains the heparin and low density lipoprotein receptor (LDLR) binding sites that contributes to the adhesive and mitogenic properties of CTGF.

Images
Immunohistochemistry

CTGF/CCN2 was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using 25 µg/mL Human CTGF/CCN2 C-Terminus Monoclonal Antibody overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit and counterstained with hematoxylin (blue).

Immunohistochemistry

CTGF/CCN2 was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using 25 µg/mL Human CTGF/CCN2 C-Terminus Monoclonal Antibody overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit and counterstained with hematoxylin (blue).