Product Details
Catalog Number: MO15140
Applications: IHC, FC
Type: Mouse IgG
Dilutions: Immunohistochemistry: 8-25 ug/ml Flow Cytometry: 2.5 ug/10^6 cells
Immunogen: HEK293 human embryonic kidney cell line transfected with human GLP-2R Met1-Ile553
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein A purified
Format B: liquid
Species Reactivity: Human
Entrez: 9340
UniProt: O95838
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$319.00Add to Cart

GLP-2R is a member of the class II glucagon-secretin G protein-coupled receptor superfamily. It is expressed on enteroendocrine cells in the gut where it mediates the positive effects of GLP2 on villus height, crypt depth and intestinal energy absorbtion. After stimulating a cAMP response, lipid raft-dependent internalization of GLP2R results in rapid desensitization to GLP2. Extracellular portions of human GLP-2R show approximately 80% amino acid identity with corresponding regions of mouse GLP-2R.

Images
Flow Cytometry

NS0 mouse myeloma cell line transfected with human GLP-2R was stained with Mouse Anti-Human GLP‑2R Monoclonal Antibody or isotype control antibody, followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody.

Flow Cytometry

NS0 mouse myeloma cell line transfected with human GLP-2R was stained with Mouse Anti-Human GLP‑2R Monoclonal Antibody or isotype control antibody, followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody.